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The stained cells are imaged on thefluorescent microscope and image algorithms are used toquantitate the amount of target proteins in different subcel-lular compartments. Like the Latin lan-guage, this epidemic provides scholars with a perfect specimen to examine:an ideal, non-evolving thing-in-a-bottle that can be placed under a meta-phorical microscope and seen from end to end, all of its connections fixedand unchanging, even if undiscovered

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Specific removal of Tregs afterTBI not only increased anti-tumor effector generation and tumor reduction, but also resultedin a reduction of Treg tumor infiltration. Assay of interstitial ammonia concentrations are reflec-tive of astrocyte function and have been shown to correlate with ICP

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Patsopoulos (2011), for instance, discusses thedistinction between an explanatory trial that—concerned primarily with issues of internalvalidity—addresses questions of treatment efficacy and a pragmatic trial that—concernedprimarily with issues of external validity—answers questions of treatment effective-ness. Both WT andmutant p53 have biological activities that are dependent on its transcriptional abil-ity, and both proteins have been demonstrated to repress expression of a number ofgenes

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An exception is HIV serocon-version meningitis, in which combination antiretroviraltherapy (cART) should be offered. For example, if the outcome isstroke and a participant suffered one 3 years after entry to the study and thendied 2 years later, their follow-up is three person-years, not five. Contained within the neck are thehyoid bone, several major blood vessels, the larynx, trachea,and the thyroid gland, which is in the anterior triangle of theneck (Fig. are the most common pathogensfollowed by Pseudomonas aeruginosa (Table 18.2).